Spurious sulfamethoxazole-trimethoprim resistance of Salmonella typhi.

نویسندگان

  • J Escamilla
  • M E Kilpatrick
  • H F Ugarte
چکیده

Several studies have identified thymidine excess in susceptibility test media as the cause of spurious resistance of various bacteria to sulfamethoxazole-trimethoprim. We document the phenomenon in Salmonella typhi and Salmonella paratyphi-A and demonstrate its occurrence in 3 of 17 (18%) lots of Mueller-Hinton agars now in use in major medical laboratories in Lima, Peru. The findings are particularly significant because sulfamethoxazole-trimethoprim is an important alternative to chloramphenicol or ampicillin for the treatment of typhoid and paratyphoid fevers.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 23 1  شماره 

صفحات  -

تاریخ انتشار 1986